Findings

What do systematic reviews say?

6 questions · 10 findings · 1 reviews · Periodontology

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No studies found 2 · 20%GRADE not reported 6 · 60%Very low 2 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
No RBF (radiographic bone defect filling) data were available for the APC + GTR versus GTR comparison.
0 studies
No studies found

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).

3 findings from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD 0.42 [-0.02, 0.86]
7 studies · 248 participants
Very low
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
9 to 12 months
MD 0.27 [-0.39, 0.93]
5 studies · 164 participants
GRADE not reported
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
3 to 6 months · Split-mouth studies only
MD 0.54 [0.18, 0.89]
3 studies · 134 participants
GRADE not reported

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
No complete pocket closure was reported (outcome addressed across included studies; no usable comparative estimate).
Studies not reported
GRADE not reported

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
No quantitative analysis regarding patients' quality of life was possible (no data).
0 studies
No studies found

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All studies in all groups reported a survival rate of 100% for the treated teeth (no comparative estimate; not GRADE-rated).
7 studies
GRADE not reported

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in probing depth (PD) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).

3 findings from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD 0.92 [-0.02, 1.86]
7 studies · 248 participants
Very low
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
3 to 6 months · Split-mouth studies only
MD 1.07 [-0.71, 2.86]
3 studies · 134 participants
GRADE not reported
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
9 to 12 months
MD 0.68 [-0.66, 2.02]
5 studies · 164 participants
GRADE not reported