Augmentation of current antidepressant (various) with quetiapine (150 mg/d to 300 mg/d) vs augmentation of current antidepressant (various) with placebo
Response (≥ 50% reduction in MADRS or HAM‐D score) ‐ Any dose · treatment‐resistant depression in adults
Augmentation of current antidepressant (various) with quetiapine… probably leads to higher response (≥ 50% reduction in MADRS or HAM‐D score) ‐ Any dose compared with augmentation of current antidepressant (various) with placebo (moderate certainty).
1 finding from 1 review
- Pharmacological interventions for treatment‐resistant depression in adults 2019 · Cochrane Headline outcomes onlyRR 1.25 [1.09, 1.44]3 studies · 977 participantsModerate