What do systematic reviews say?

Atypical vs Typical antipsychotics

Atypical showed no clear difference in diabetes (ADA criteria) (6 weeks) compared with typical antipsychotic medications (low certainty).

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 0.5 [0.03, 7.73]
  1 study · 93 participants
  Low

Atypical vs Typical antipsychotics

Atypical showed no clear difference in drop‐outs (6 to 54 weeks) compared with typical antipsychotic medications (low certainty).

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 1.31 [0.63, 2.69]
  2 studies · 144 participants
  Low

Atypical vs Typical antipsychotics

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 211 participants
  Moderate

Atypical vs Typical antipsychotics

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 141 participants
  Moderate