Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

106 questions · 115 findings · 12 reviews

No studies found 27 · 23.5%GRADE not reported 13 · 11.3%Very low 45 · 39.1%Low 17 · 14.8%Moderate 8 · 7%High 5 · 4.3%

Aspirin vs placebo

Total mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in total mortality compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Cardiovascular mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in cardiovascular mortality compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Non‐fatal cardiovascular events · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin may leads to lower non‐fatal cardiovascular events compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Major bleedinga · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin leads to higher major bleedinga compared with placebo (high certainty).

1 finding from 1 review

Aspirin vs placebo

Cardiovascular events · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin may leads to lower all cardiovascular events compared with placebo (low certainty).

1 finding from 1 review

Heparin plus aspirin vs aspirin

Adverse events in the mother ‐ Bleeding · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

Heparin plus aspirin showed no clear difference in adverse events in the mother ‐ Bleeding compared with aspirin (low certainty).

1 finding from 1 review