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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Eyes and Vision

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 4 · 57.1%High 0 · 0%

'As needed' administration (e.g. based on pain scales) vs monthly injections

Gain of 3 or more lines of visual acuity · people with neovascular age‐related macular degeneration

As needed may leads to lower gain of ≥ 15 letters visual acuity at 1 year compared with monthly injections (low certainty).

1 finding from 1 review

'As needed' administration (e.g. based on pain scales) vs monthly injections

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · people with neovascular age‐related macular degeneration
1 finding from 1 review

'As needed' administration (e.g. based on pain scales) vs monthly injections

Proportion of participants with endophthalmitis · people with neovascular age‐related macular degeneration

As needed probably leads to lower endophthalmitis (ocular adverse event) compared with monthly injections (moderate certainty).

1 finding from 1 review