What do systematic reviews say?

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal sepsis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  RR 2.37 [0.1, 56.41]
  1 study · 75 participants
  Very low

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) showed no clear difference in maternal endometritis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (low certainty).

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  RR 1.1 [0.76, 1.6]
  7 studies · 1161 participants
  Low

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal wound infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.78 [0.32, 1.9]
  4 studies · 543 participants
  Very low

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal urinary tract infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.64 [0.11, 3.73]
  4 studies · 496 participants
  Very low

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal composite adverse effects compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

• Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.96 [0.09, 10.5]
  2 studies · 468 participants
  Very low