Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Gynaecology and Fertility

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Live birth rate per couple · patients with male subfertility

It is very uncertain whether antioxidants changes live birth rate per couple randomised compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antioxidants for male subfertility 2022 · Cochrane Headline outcomes only
OR 1.43 [1.07, 1.91]
12 studies · 1283 participants
Very low

Clinical pregnancy rate · patients with male subfertility

Antioxidants may leads to higher clinical pregnancy rate per couple randomised compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antioxidants for male subfertility 2022 · Cochrane Headline outcomes only
OR 1.89 [1.45, 2.47]
20 studies · 1706 participants
Low

Adverse events ‐ Miscarriage · patients with male subfertility

It is very uncertain whether antioxidants changes adverse events ‐ Miscarriage compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antioxidants for male subfertility 2022 · Cochrane Headline outcomes only
OR 1.46 [0.75, 2.83]
6 studies · 664 participants
Very low

Gastrointestinal adverse events · patients with male subfertility

Antioxidants may leads to higher adverse events ‐ Gastrointestinal compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antioxidants for male subfertility 2022 · Cochrane Headline outcomes only
OR 2.7 [1.46, 4.99]
16 studies · 1355 participants
Low