What do systematic reviews say?

Antioestrogen vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 567 participants
  GRADE not reported

Antioestrogen vs antioestrogen

It is very uncertain whether antioestrogen changes clomiphene citrate plus tamoxifen versus clomiphene citrate ‐… compared with antioestrogen (very low certainty).

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 3.32 [0.12, 91.6]
  1 study · 20 participants
  Very low
• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 1.3 [0.92, 1.85]
  5 studies · 757 participants
  Low

Antioestrogen vs antioestrogen

Antioestrogen showed no clear difference in clomiphene citrate versus tamoxifen ‐ Live birth rate compared with antioestrogen (low certainty).

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 1.24 [0.59, 2.62]
  2 studies · 195 participants
  Low

Antioestrogen vs antioestrogen

Antioestrogen showed no clear difference in clomiphene citrate versus tamoxifen ‐ Miscarriage rate compared with antioestrogen (low certainty).

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 1.81 [0.8, 4.12]
  4 studies · 653 participants
  Low

Antioestrogen vs antioestrogen

It is very uncertain whether antioestrogen changes clomiphene citrate versus tamoxifen ‐ Multiple pregnancy compared with antioestrogen (very low certainty).

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 2.34 [0.34, 16.04]
  3 studies · 567 participants
  Very low

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Antioestrogen plus medical adjunct vs antioestrogen

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  OR 1.03 [0.48, 2.21]
  2 studies · 174 participants
  Low

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low