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Evidence found and GRADE certainty

168 questions · 181 findings · 19 reviews

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No studies found 63 · 34.8%GRADE not reported 49 · 27.1%Very low 39 · 21.5%Low 14 · 7.7%Moderate 11 · 6.1%High 5 · 2.8%

Mucoadhesive disk (carbomer/triglycerides + antimicrobial agents) vs Placebo disk

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
  • Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
    Kerr 2010 (crossover, high risk of bias): no difference in oral dryness between active and placebo disks; increase in subjective oral moistness with both, persisting up to 2 weeks after last use (likely carryover);…
    1 study
    GRADE not reported

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Clinical attachment level (CAL) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower clinical attachment level compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Low birth weight (< 2.5 kg) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes low birth weight < 2500 g compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Mean birth weight · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Gestational age (preterm birth < 37 weeks) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes gestational age (preterm birth < 37 weeks) compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

3 findings from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Pre‐eclampsia · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Low birth weight < 1500 g · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes low birth weight < 1500 g compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Percentage of bleeding on probing (BOP) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower bleeding on probing compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Maternal death · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Gingival index (GI) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… showed no clear difference in gingival index compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Adverse effects of therapy · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Preterm birth < 35 weeks · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Probing pocket depth · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower probing depth compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Small‐for‐gestational age · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Gingival index (GI) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower gingival index (GI) compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

HbA1c (glycated haemoglobin), change · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… probably leads to lower hbA1c (glycated haemoglobin), change compared with no active intervention/usual care (moderate certainty).

1 finding from 1 review

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Quality of life indicators · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Plaque index (PI) / oral hygiene · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower plaque index (PI) / oral hygiene compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review