'Other' antidepressants vs placebo
Quality of sleep · adults with insomnia
1 finding from 1 review
- no estimate extracted3 studies · 370 participantsModerate
Findings
What do systematic reviews say?
17 questions · 18 findings · 3 reviews · Common Mental Disorders
No studies found 3 · 16.7%GRADE not reported 0 · 0%Very low 5 · 27.8%Low 9 · 50%Moderate 1 · 5.6%High 0 · 0%
'Other' antidepressants vs placebo
Adverse events · adults with insomnia
1 finding from 1 review
- no estimate extracted2 studies · 217 participantsLow
'Other' antidepressants vs placebo
Sleep efficiency · adults with insomnia
1 finding from 1 review
- no estimate extracted2 studies · 169 participantsLow
Antidepressants vs any other pharmacological intervention
Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression response (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
- RR 0.98 [0.76, 1.27]Studies not reportedVery low
Antidepressants vs any other pharmacological intervention
Depression remission · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).
2 findings from 1 review
- RR 0.98 [0.68, 1.41]Studies not reportedVery low
- no estimate extractedStudies not reportedLow
Antidepressants vs any other pharmacological intervention
Adverse events · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs any other pharmacological intervention
Depression response (early phase, < 5 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
- no estimate extractedStudies not reportedLow
Antidepressants vs any other pharmacological intervention
Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Antidepressants vs any other pharmacological intervention
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
- RR 1.74 [0.99, 3.06]Studies not reportedVery low
Antidepressants vs any other pharmacological intervention
Child‐related outcomes · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Tricyclic antidepressants vs another medication
Severity/intensity of MUPS (post‐treatment score on self report scales) Different self report scales (VAS‐Pain, SCL‐90‐R Somatisation Subscore) · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 177 participantsLow
Tricyclic antidepressants vs another medication
Acceptability · somatoform disorders in adults
Tricyclic antidepressants showed no clear difference in acceptability (all‐cause drop‐outs4) compared with another medication (low certainty).
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyRR 1.48 [0.59, 3.72]8 studies · 556 participantsLow
Tricyclic antidepressants vs another medication
Anxiety · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 255 participantsVery low
Tricyclic antidepressants vs another medication
Depression (post‐treatment score on self report and clinician‐rated scales) Different self report and clinician‐rated scales (HDRS, BDI) · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 395 participantsLow
Tricyclic antidepressants vs another medication
Adverse effects (drop‐outs due to adverse effects4) · somatoform disorders in adults
Tricyclic antidepressants showed no clear difference in adverse effects (drop‐outs due to adverse effects4) compared with another medication (low certainty).
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyRR 2.37 [0.39, 14.28]8 studies · 556 participantsLow
Tricyclic antidepressants vs another medication
Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Tricyclic antidepressants showed no clear difference in treatment response (post‐treatment score on self report and… compared with another medication (low certainty).
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyRR 0.93 [0.73, 1.19]2 studies · 130 participantsLow
Tricyclic antidepressants vs another medication
Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability · somatoform disorders in adults
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found