Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

120 questions · 126 findings · 18 reviews

No studies found 14 · 11.1%GRADE not reported 3 · 2.4%Very low 40 · 31.7%Low 47 · 37.3%Moderate 20 · 15.9%High 2 · 1.6%

Antidepressants vs placebo

Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in depression response (acute, 5 ≤ 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Depression remission · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in depression remission (acute, 5 ≤ 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Acceptability ‐ total dropouts · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in treatment acceptability ‐ dropouts compared with placebo (low certainty).

1 finding from 1 review