Findings

What do systematic reviews say?

73 questions · 74 findings · 6 reviews

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No studies found 16 · 21.6%GRADE not reported 2 · 2.7%Very low 33 · 44.6%Low 18 · 24.3%Moderate 4 · 5.4%High 1 · 1.4%

Antidepressants vs placebo

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 225 participants
Very low

Antidepressants vs placebo

Gambling expenditure · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 144 participants
Low

Antidepressants vs placebo

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Antidepressants vs opioid antagonists

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Antidepressants vs opioid antagonists

Gambling expenditure ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs opioid antagonists

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs opioid antagonists

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs opioid antagonists

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 62 participants
Very low

Antidepressants vs opioid antagonists

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 62 participants
Very low

Antidepressants vs opioid antagonists

Functional impairment ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Antidepressants vs opioid antagonists

Responder status · treatment of disordered and problem gambling

It is very uncertain whether antidepressants changes responder status compared with opioid antagonists (very low certainty).

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
RR 1.01 [0.54, 1.87]
1 study · 36 participants
Very low

Antidepressants vs mood stabilisers

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Antidepressants vs mood stabilisers

Gambling expenditure ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs mood stabilisers

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs mood stabilisers

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs mood stabilisers

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Very low

Antidepressants vs mood stabilisers

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Very low

Antidepressants vs mood stabilisers

Functional impairment ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs mood stabilisers

Responder status · treatment of disordered and problem gambling

It is very uncertain whether antidepressants changes responder status compared with mood stabilisers (very low certainty).

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
RR 0.63 [0.29, 1.33]
1 study · 31 participants
Very low