Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

Antidepressants may leads to lower failure to respond compared with placebo (low certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.72 [0.66, 0.79]
30 studies · 6500 participants
Low

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

Tricyclic antidepressants probably leads to lower failure to respond compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.73 [0.63, 0.86]
9 studies · 829 participants
Moderate