Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

249 questions · 257 findings · 31 reviews

No studies found 52 · 20.2%GRADE not reported 5 · 1.9%Very low 81 · 31.5%Low 77 · 30%Moderate 34 · 13.2%High 8 · 3.1%

Antidepressants vs any other pharmacological intervention

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).

2 findings from 1 review

Antidepressants vs placebo

Acceptability ‐ total dropouts · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in treatment acceptability ‐ dropouts compared with placebo (low certainty).

1 finding from 1 review