Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Antibody (T cell) vs steroids

Graft loss or death with a functioning graft · kidney transplant recipients: first rejection episode

Antibody (T cell) showed no clear difference in graft loss or death with a functioning graft compared with steroid (stratified by antibody type) (low certainty).

1 finding from 1 review

Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 0.84 [0.58, 1.22]
8 studies · 490 participants
Low

Antibody (T cell) + steroid vs steroids

Graft loss or death with a functioning graft · kidney transplant recipients: first rejection episode

It is very uncertain whether antibody (T cell) + steroid changes graft loss or death with a functioning graft compared with steroid alone (very low certainty).

1 finding from 1 review

Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 0.35 [0.02, 5.14]
2 studies · 52 participants
Very low

T‐cell antibody induction vs corticosteroid induction

Graft loss including death · liver transplant recipients

T‐cell antibody induction showed no clear difference in graft loss Graft loss (including death with a functioning graft) at… compared with corticosteroid induction (low certainty).

1 finding from 1 review

Antibody induction versus corticosteroid induction for liver transplant recipients 2014 · Cochrane Headline outcomes only
RR 1.12 [0.82, 1.53]
10 studies · 1589 participants
Low