Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Injuries

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Single‐dose antibiotic vs 24 hours of antibiotics

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether single dose of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
RR 1.48 [0.87, 2.52]
1 study · 360 participants
Very low

Single‐dose antibiotic vs 24 hours of antibiotics

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 360 participants
Very low

Single‐dose antibiotic vs 24 hours of antibiotics

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether single dose of antibiotics changes intra‐abdominal infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
RR 0.76 [0.25, 2.32]
1 study · 360 participants
Very low

More than 24 hours of antibiotics vs 24 hours of antibiotics

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
RR 1 [0.81, 1.23]
7 studies · 1261 participants
Very low

More than 24 hours of antibiotics vs 24 hours of antibiotics

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes mortality compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
OR 1.67 [0.73, 3.82]
7 studies · 1261 participants
Very low

More than 24 hours of antibiotics vs 24 hours of antibiotics

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes intra‐abdominal infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
RR 1.23 [0.84, 1.8]
6 studies · 1111 participants
Very low