Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Colorectal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 85.7%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Appendectomy in the antibiotic group · adults with uncomplicated appendicitis

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1396 participants
Very low

All‐cause mortality · adults with uncomplicated appendicitis

It is very uncertain whether antibiotics changes mortality compared with surgery (very low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
OR 0.51 [0.05, 4.95]
5 studies · 2377 participants
Very low

Treatment success (caries lesion arrest or restoration survival) · adults with uncomplicated appendicitis

Antibiotics may leads to lower success of treatment compared with surgery (low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
RR 0.91 [0.87, 0.96]
7 studies · 2471 participants
Low

Clostridium difficile diarrhoea · adults with uncomplicated appendicitis

It is very uncertain whether antibiotics changes clostridium difficile diarrhoea compared with surgery (very low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
OR 0.97 [0.24, 3.89]
3 studies · 1552 participants
Very low

Intra‐abdominal fluid collection, abscess · adults with uncomplicated appendicitis

It is very uncertain whether antibiotics changes intra‐abdominal abscess or collection compared with surgery (very low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
RR 1.58 [0.61, 4.07]
6 studies · 1831 participants
Very low

Reoperation · adults with uncomplicated appendicitis

It is very uncertain whether antibiotics changes reoperation compared with surgery (very low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
OR 0.13 [0.01, 2.16]
1 study · 492 participants
Very low

Length of hospital stay · adults with uncomplicated appendicitis

It is very uncertain whether antibiotics changes length of hospital stay (days) compared with surgery (very low certainty).

1 finding from 1 review

Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes only
MD 0.54 [0.06, 1.01]
11 studies · 3192 participants
Very low