Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

79 questions · 88 findings · 14 reviews

No studies found 45 · 51.1%GRADE not reported 15 · 17%Very low 13 · 14.8%Low 10 · 11.4%Moderate 5 · 5.7%High 0 · 0%

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

New renal parenchymal defects (scars and thinning) on IVP: unit of analysis (children) at 4 to 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

Surgical reimplantation of ureters plus antibiotics showed no clear difference in new renal parenchymal defects (scars and thinning) on IVP: unit of… compared with antibiotics alone (moderate certainty).

1 finding from 1 review

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

Correction of VUR: unit of analysis (children) after 3 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes correction of VUR: unit of analysis (children) after 3 years:… compared with antibiotics alone (very low certainty).

1 finding from 1 review

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

Febrile UTI by 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).

1 finding from 1 review

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)

It is very uncertain whether combined HBO and perioperative antibiotics prior to dental implant… changes incidence of ORN compared with antibiotics alone prior to dental implant therapy (very low certainty).

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Cure: short‐term success · patients on maintenance HD with CRBSI

It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: short‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Cure: long‐term success · patients on maintenance HD with CRBSI

It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: long‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Stenosis or thrombosis of vascular access site after catheter removal · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Development of antibiotic resistance · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review