Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

594 questions · 624 findings · 70 reviews

No studies found 151 · 24.2%GRADE not reported 53 · 8.5%Very low 174 · 27.9%Low 129 · 20.7%Moderate 82 · 13.1%High 35 · 5.6%

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Patient satisfaction: delayed (prescription collection) versus no antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to higher patient satisfaction: delayed (prescription collection) versus no… compared with no antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Antibiotic use: delayed (all strategies) versus immediate antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to lower antibiotic use: delayed (all strategies) versus immediate antibiotics compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Patient satisfaction: delayed (all strategies) versus immediate antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics showed no clear difference in patient satisfaction: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Reconsultations · respiratory infections

Summary of findings table ‐ Delayed antibiotics showed no clear difference in reconsultation rate: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Antibiotic use: delayed (all strategies) versus no antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to higher antibiotic use: delayed (all strategies) versus no antibiotics compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Pain ‐ pain at 24 hours · children with acute otitis media

Antibiotics showed no clear difference in pain ‐ pain at 24 hours compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Pain ‐ pain at 2 to 3 days · children with acute otitis media

Antibiotics leads to lower pain ‐ pain at 2 to 3 days compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Pain ‐ pain at 4 to 7 days · children with acute otitis media

Antibiotics showed no clear difference in pain ‐ pain at 4 to 7 days compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Pain ‐ pain at 10 to 12 days · children with acute otitis media

Antibiotics probably leads to lower pain ‐ pain at 10 to 12 days compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Vomiting, diarrhoea or rash · children with acute otitis media

Antibiotics leads to higher vomiting, diarrhoea or rash compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Abnormal tympanometry ‐ 2 to 4 weeks · children with acute otitis media

Antibiotics leads to lower abnormal tympanometry ‐ 2 to 4 weeks compared with placebo (high certainty).

1 finding from 1 review