Findings

What do systematic reviews say?

2 questions · 3 findings · 1 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Antibiotic prophylaxis vs placebo, no treatment or surveillance only

Number of participants with symptomatic UTI · primary VUR

Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).

2 findings from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 0.77 [0.54, 1.09]
9 studies · 1667 participants
Low
Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 0.85 [0.4, 1.79]
3 studies · 943 participants
Moderate

Antibiotic prophylaxis vs placebo, no treatment or surveillance only

Febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis · primary VUR

Antibiotic prophylaxis showed no clear difference in febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 0.83 [0.56, 1.21]
9 studies · 1667 participants
Low