What do systematic reviews say?

Antacids vs sucralfate

Antacids showed no clear difference in clinically important upper GI bleeding compared with sucralfate (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1 [0.72, 1.39]
  16 studies · 1772 participants
  Low