What do systematic reviews say?

Anaerobic coverage only vs gram‐negative and anaerobic coverage

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐negative and anaerobic coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 1.02 [0.68, 1.52]
  4 studies · 523 participants
  Very low

Anaerobic coverage only vs gram‐negative and anaerobic coverage

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 417 participants
  Very low

Anaerobic coverage only vs gram‐negative and anaerobic coverage

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐negative and anaerobic coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 1.17 [0.59, 2.32]
  3 studies · 437 participants
  Very low

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 1.46 [0.79, 2.71]
  4 studies · 395 participants
  Very low

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 309 participants
  Very low

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 2.46 [0.66, 9.14]
  3 studies · 309 participants
  Very low

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive and gram‐negative coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 0.68 [0.32, 1.45]
  2 studies · 160 participants
  Very low

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 160 participants
  Very low

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive and gram‐negative coverage (very low certainty).

• Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
  RR 0.56 [0.15, 2.07]
  1 study · 66 participants
  Very low