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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

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An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission at 28 weeks among those whose diagnostic testing was negative at 2 weeks after birth · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… probably leads to lower HIV transmission at 28 weeks among those whose diagnostic testing… compared with 1 week of antiretroviral prophylaxis (moderate certainty).

1 finding from 1 review

An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

Infant mortality at 28 weeks among those whose diagnostic testing was negative at 2 weeks after birth · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… showed no clear difference in infant mortality at 28 weeks among those whose diagnostic testing… compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review

An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… probably leads to lower HIV transmission or death at 28 weeks among those whose diagnostic… compared with 1 week of antiretroviral prophylaxis (moderate certainty).

1 finding from 1 review

An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

Infants with Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… showed no clear difference in infants with Severe Adverse Events compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review

An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

Mothers with Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… may leads to higher mothers with Severe Adverse Events compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review