Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · HIV/AIDS

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 1 · 25%High 0 · 0%

An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission at 28 weeks among those whose diagnostic testing was negative at 2 weeks after birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 28 weeks may leads to lower HIV transmission at 28 weeks among those whose diagnostic testing… compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review

An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis

Infant mortality at 28 weeks among those whose diagnostic testing was negative at 2 weeks after birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 28 weeks showed no clear difference in infant mortality at 28 weeks among those whose diagnostic testing… compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review

An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 28 weeks probably leads to lower HIV transmission or death at 28 weeks among those whose diagnostic… compared with 1 week of antiretroviral prophylaxis (moderate certainty).

1 finding from 1 review

An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis

Infants with Severe Adverse Events · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 28 weeks showed no clear difference in infants with Severe Adverse Events compared with 1 week of antiretroviral prophylaxis (low certainty).

1 finding from 1 review