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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Altered WBRT fractionation schedules vs WBRT control

Overall survival: higher‐dose WBRT vs control (3000 cGy/10 daily fractions)No. of participants: 846(4 RCTs) · patients with newly diagnosed multiple brain metastases

Altered WBRT fractionation schedules showed no clear difference in overall survival: higher‐dose WBRT vs control (3000 cGy/10 daily… compared with WBRT control (moderate certainty).

1 finding from 1 review

Altered WBRT fractionation schedules vs WBRT control: neurological function improvement

Neurological function improvement: higher‐dose WBRT vs control dose WBRT (3000 cGy/10 fractions)No. of participants: 1480(4 RCTs) · patients with newly diagnosed multiple brain metastases

Altered WBRT fractionation schedules showed no clear difference in neurological function improvement: higher‐dose WBRT vs control dose… compared with WBRT control: neurological function improvement (moderate certainty).

1 finding from 1 review