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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 1 · 12.5%Very low 0 · 0%Low 1 · 12.5%Moderate 3 · 37.5%High 3 · 37.5%

Alpha2‐adrenergic agonist vs control

Acute stroke (within 30‐days after surgery: new focal neurologic deficit with signs and symptoms lasting longer than 24 hours) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists may leads to lower acute stroke (within 30‐days after surgery: new focal neurologic… compared with control (low certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

All‐cause mortality (within 30‐days after surgery: any reported death) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in all‐cause mortality (within 30‐days after surgery: any reported death) compared with control (moderate certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

Myocardial infarction (within 30‐days after surgery: sudden death or death resulting from a primarily identifiable cardiac cause) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in myocardial infarction (within 30‐days after surgery: sudden death or… compared with control (moderate certainty).

1 finding from 1 review