Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 25%Very low 0 · 0%Low 0 · 0%Moderate 1 · 25%High 2 · 50%

Alpha2‐adrenergic agonist vs control

All‐cause mortality (within 30‐days after surgery: any reported death) · adults undergoing non‐cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 14081 participants
High

Alpha2‐adrenergic agonist vs control

All‐cause mortality (within 30‐days after surgery: any reported death) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in all‐cause mortality (within 30‐days after surgery: any reported death) compared with control (moderate certainty).

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
RR 0.52 [0.26, 1.04]
16 studies · 1947 participants
Moderate

Alpha2‐adrenergic agonist vs control

Cardiac mortality · adults undergoing cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
GRADE not reported

Alpha2‐adrenergic agonist vs control

Cardiac mortality · adults undergoing non‐cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 12525 participants
High