Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 3 reviews

No studies found 5 · 55.6%GRADE not reported 0 · 0%Very low 1 · 11.1%Low 1 · 11.1%Moderate 2 · 22.2%High 0 · 0%

Aldosterone antagonists vs placebo or usual care

All cardiovascular death · people with chronic kidney disease requiring dialysis

Aldosterone antagonists (spironolactone or eplerenone) probably leads to lower death (cardiovascular) compared with control (placebo or standard care) (moderate certainty).

1 finding from 1 review