Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 3 · 50%High 0 · 0%

All‐cause mortality (at end of

Albumin and fresh frozen plasma showed no clear difference in all‐cause mortality (at end of compared with crystalloid (moderate certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 0.98 [0.92, 1.06]
20 studies · 13047 participants
Moderate

All‐cause mortality (within 90 days)

Albumin and fresh frozen plasma showed no clear difference in all‐cause mortality (within 90 days) compared with crystalloid (moderate certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 0.98 [0.92, 1.04]
10 studies · 12492 participants
Moderate

All‐cause mortality (within 30 days)

Albumin and fresh frozen plasma showed no clear difference in all‐cause mortality (within 30 days) compared with crystalloid (moderate certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 0.99 [0.93, 1.06]
10 studies · 12506 participants
Moderate

Transfusion of blood products

It is very uncertain whether albumin and fresh frozen plasma changes transfusion of blood products compared with crystalloid (very low certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 1.31 [0.95, 1.8]
3 studies · 290 participants
Very low

Renal replacement therapy

Albumin and fresh frozen plasma showed no clear difference in renal replacement therapy compared with crystalloid (low certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 1.11 [0.96, 1.27]
2 studies · 3028 participants
Low

Adverse events

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low