Add‐on lamotrigine vs placebo
50% or greater reduction in seizure frequency · people with drug‐resistant generalised tonic‐clonic seizures
Add‐on lamotrigine may leads to higher 50% or greater reduction in seizure frequency compared with placebo (low certainty).
1 finding from 1 review
- Lamotrigine add‐on therapy for drug‐resistant generalised tonic‐clonic seizures 2020 · Cochrane Headline outcomes onlyRR 1.88 [1.43, 2.45]2 studies · 270 participantsLow