Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 1 · 16.7%Moderate 3 · 50%High 1 · 16.7%

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

End of treatment ‐ heterozygous · people who smoke

It is very uncertain whether active NRT changes end of treatment ‐ heterozygous compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs1051730 ‐ non‐Hispanic white

Abstinence at end of treatment ‐ heterozygous · people who smoke

Active NRT probably leads to higher abstinence at end of treatment ‐ heterozygous compared with placebo ‐ rs1051730 ‐ non‐Hispanic white (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

End of treatment ‐ heterozygous or homozygous minor · people who smoke

Active NRT showed no clear difference in end of treatment ‐ heterozygous or homozygous minor compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American

Abstinence at end of treatment ‐ heterozygous or homozygous minor · people who smoke

Active NRT probably leads to lower abstinence at end of treatment ‐ heterozygous or homozygous minor compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review