Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 30%Low 4 · 40%Moderate 3 · 30%High 0 · 0%

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ heterozygous · people who smoke

Active NRT showed no clear difference in 6‐Month abstinence ‐ heterozygous compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

6‐Month abstinence ‐ homozygous major · people who smoke

It is very uncertain whether active NRT changes 6‐Month abstinence ‐ homozygous major compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ homozygous major · people who smoke

It is very uncertain whether active NRT changes 6‐month abstinence ‐ homozygous major compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ homozygous minor · people who smoke

It is very uncertain whether active NRT changes 6‐Month abstinence ‐ homozygous minor compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

6‐Month abstinence ‐ heterozygous or homozygous minor · people who smoke

Active NRT showed no clear difference in 6‐Month abstinence ‐ heterozygous or homozygous minor compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review