Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Vascular

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No studies found 2 · 33.3%GRADE not reported 3 · 50%Very low 0 · 0%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Thrombosis · people with antiphospholipid antibodies and no history of thrombosis

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
GRADE not reported

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Bleeding ‐ major/excessive · people with antiphospholipid antibodies and no history of thrombosis

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
GRADE not reported

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Subcutaneous bruises · people with antiphospholipid antibodies and no history of thrombosis

ASA + high‐dose LMWH showed no clear difference in subcutaneous bruises compared with ASA + low‐dose LMWH or UFH (low certainty).

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
RR 1 [0.34, 2.93]
2 studies · 120 participants
Low

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

All‐cause mortality · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Quality of life · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Adverse events other than bleeding · people with antiphospholipid antibodies and no history of thrombosis

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported