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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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ALK inhibitor vs any cytotoxic chemotherapy

Progression‐free survival in people with central nervous system disease · advanced anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer

ALK inhibitor leads to lower progression‐free survival in people with central nervous system… compared with any cytotoxic chemotherapy (high certainty).

1 finding from 1 review

Next‐generation ALK inhibitor vs crizotinib

Progression‐free survival in people with central nervous system disease · advanced anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer

Next‐generation ALK inhibitor leads to lower progression‐free survival in people with central nervous system… compared with crizotinib (high certainty).

1 finding from 1 review