Findings

What do systematic reviews say?

46 questions · 46 findings · 4 reviews

No studies found 3 · 6.5%GRADE not reported 1 · 2.2%Very low 20 · 43.5%Low 16 · 34.8%Moderate 6 · 13%High 0 · 0%

Failure to maintain remission · Patients with quiescent ulcerative colitis

It is very uncertain whether 6‐Mercaptopurine changes failure to maintain remission compared with 5‐ASA (very low certainty).

1 finding from 1 review

Azathioprine and 6‐mercaptopurine for maintenance of remission in ulcerative colitis 2016 · Cochrane Headline outcomes only
RR 0.53 [0.31, 0.9]
1 study · 22 participants
Very low

Failure to maintain remission · Patients with quiescent ulcerative colitis

It is very uncertain whether 6‐Mercaptopurine changes failure to maintain remission compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine and 6‐mercaptopurine for maintenance of remission in ulcerative colitis 2016 · Cochrane Headline outcomes only
RR 0.55 [0.31, 0.95]
1 study · 26 participants
Very low

Maintenance of remission · maintenance of remission in Crohn's disease

It is very uncertain whether 6‐Mercaptopurine changes maintenance of remission compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.94 [0.47, 1.85]
1 study · 31 participants
Very low

Adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether 6‐Mercaptopurine changes adverse events compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.65 [0.31, 1.38]
1 study · 57 participants
Very low

Withdrawals due to adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether 6‐Mercaptopurine changes withdrawals due to adverse events compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.68 [0.17, 2.75]
1 study · 57 participants
Very low

Serious adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether 6‐Mercaptopurine changes serious adverse events compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.68 [0.17, 2.75]
1 study · 57 participants
Very low