Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Colorectal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

5‐ASA vs control (all trials)

Recurrence of diverticulitis · patients with the need for management of diverticulitis

It is very uncertain whether 5‐ASA changes recurrence of diverticulitis compared with control (all trials) (very low certainty).

1 finding from 1 review

Mesalamine (5‐ASA) for the prevention of recurrent diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.69 [0.43, 1.09]
7 studies · 1805 participants
Very low

5‐ASA vs control (all trials)

Number of participants with adverse events (epigastric pain, nausea, diarrhoea) · patients with the need for management of diverticulitis

5‐ASA showed no clear difference in number of participants with adverse events (epigastric pain, nausea,… compared with control (all trials) (moderate certainty).

1 finding from 1 review

Mesalamine (5‐ASA) for the prevention of recurrent diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.98 [0.91, 1.06]
5 studies · 1421 participants
Moderate