Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

1500 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Caries increment, tooth index D(M)FT · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
12 months
No studies reported poolable d(m)ft increment; Cahen 1982 reported a df-rate of 18.25% (n=708) in the 0 ppm group vs 13.64% (n=632, 1500 ppm SMFP) and 9.37% (n=668, amine fluoride) groups.
1 study
GRADE not reported

1450 to 1500 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1450 to 1500 ppm F toothpaste probably leads to lower caries increment, tooth index D(M)FT compared with non-fluoride (0 ppm F) placebo toothpaste (moderate certainty).

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
SMD -0.39 [-0.49, -0.28]
4 studies
Moderate

1450 to 1500 ppm F toothpaste vs 1000 to 1250 ppm F toothpaste

Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1450 to 1500 ppm F toothpaste may leads to lower caries increment, tooth index D(M)FT compared with 1000 to 1250 ppm F toothpaste (low certainty).

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
SMD -0.13 [-0.23, -0.02]
4 studies
Low

1450 to 1500 ppm F toothpaste vs 440 to 550 ppm F toothpaste

Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1450 to 1500 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 440 to 550 ppm F toothpaste (low certainty).

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
SMD -0.2 [-0.45, 0.04]
Studies not reported
Low

1450 to 1500 ppm F toothpaste vs 250 ppm F toothpaste

Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1450 to 1500 ppm F toothpaste may leads to lower caries increment, tooth index D(M)FT compared with 250 ppm F toothpaste (low certainty).

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
SMD -0.28 [-0.47, -0.09]
Studies not reported
Low