Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

Δ9‐Tetrahydrocannabinol preparation vs placebo

Abstinence · cannabis dependence

Δ9‐Tetrahydrocannabinol preparation showed no clear difference in participants abstinent at end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.98 [0.64, 1.52]
3 studies · 305 participants
Moderate

Δ9‐Tetrahydrocannabinol preparation vs placebo

Participants with at least some Side Effects · cannabis dependence

Δ9‐Tetrahydrocannabinol preparation showed no clear difference in participants experiencing adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.02 [0.89, 1.17]
3 studies · 318 participants
Moderate

Δ9‐Tetrahydrocannabinol preparation vs placebo

Withdrawals due to adverse events · cannabis dependence

Δ9‐Tetrahydrocannabinol preparation showed no clear difference in participants withdrawn due to adverse effects compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 2.72 [0.51, 14.59]
3 studies · 318 participants
Low

Δ9‐Tetrahydrocannabinol preparation vs placebo

Completion of scheduled treatment · cannabis dependence

Δ9‐Tetrahydrocannabinol preparation showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.1 [0.88, 1.37]
4 studies · 369 participants
Low