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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

87 questions in 18 reviews · Implants and prosthodontics

current versions
No studies 87 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Patient satisfaction · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies reported data for this outcome.NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Quality of life · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Change in gingival recession (REC) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Outcome NR · Adults (> 18 years) with peri-implant mucositis, receiving supportive treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Planned comparison; no studies met the inclusion criteria. The review found only one study of peri-implant disease (peri-implant mucositis, active treatment) and no studies including people with peri-implantitis…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Outcome NR · Adults (> 18 years) with peri-implantitis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Planned comparison; no studies met the inclusion criteria. The review found only one study of peri-implant disease (peri-implant mucositis, active treatment) and no studies including people with peri-implantitis…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Pocket closure · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment · 6 months (change from baseline)
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies measured this outcome at 6 months (SoF row labeled 'Change in pocket depth from baseline to 6 months after initial treatment').NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Outcome NR · Adults (> 18 years) with peri-implantitis, receiving supportive treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Planned comparison; no studies met the inclusion criteria. The review found only one study of peri-implant disease (peri-implant mucositis, active treatment) and no studies including people with peri-implantitis…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Patient satisfaction · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Quality of life · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies reported data for this outcome.NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Any adverse effect related to aPDT · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Quality of life · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies reported data for this outcome.NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Pocket closure · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Patient satisfaction · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies reported data for this outcome.NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT
Change in clinical attachment level (CAL) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies…NRNo studies
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Pocket closure · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care · 6 months (change from baseline)
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane
No studies measured this outcome at 6 months (SoF row labeled 'Change in pocket depth from baseline to 6 months after treatment'); no studies reported these data at six months after treatment.NRNo studies
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with xenograft (bone graft) vs Extraction alone
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft vs ARP with xenograft
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs ARP with xenograft
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft vs ARP with xenograft
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
Tooth- and tissue-supported removable partial denture: dual-impression technique with a different material vs An alternative dual-impression technique with a different material
Outcome NR · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
We did not find any trials for this comparison.0 studiesNo studies
Alginate (two stage-two step final/wash impression) vs Silicone elastomer (two stage-two step)
Number of border adjustments and sore spots after insertion of denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method
Number of border adjustments and sore spots after insertion of denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Ball (stud) attachment system vs Telescopic attachment system
Prosthodontic success (specific categorization) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Short term (1 to 3 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
no estimate extractedNRNo studies
Wax (fluid wax), two stage-two step selective pressure final impression vs Polysulfide rubber (elastomer)
Participant-reported oral health-related quality of life (OHIP-EDENT) · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Wax (fluid wax), two stage-two step selective pressure final impression vs Polysulfide rubber (elastomer)
Participant-reported quality of the denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Ball (stud) attachment system vs Telescopic attachment system
Cost (treatment time and/or material costs) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
no estimate extractedNRNo studies
Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether
Participant-reported oral health-related quality of life · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Tooth-supported removable partial denture: same impression material, different final-impression technique vs The same material with an alternative final-impression technique
Outcome NR · Partially edentulous people requiring a removable partial denture
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
We did not find any trials for this comparison.0 studiesNo studies
Tooth-supported removable partial denture: different impression material, same final-impression technique vs The same technique with an alternative final-impression material
Outcome NR · Partially edentulous people requiring a removable partial denture
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
We did not find any trials for this comparison.0 studiesNo studies
Any attachment system for maxillary implant overdentures vs A different attachment system for maxillary implant overdentures
Outcome NR · Edentulous adults receiving maxillary implant overdentures
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
no estimate extractedNRNo studies
Ball (stud) attachment system vs Magnetic attachment system
Patient preference (cross-over trials) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
no estimate extractedNRNo studies
Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)
Periodontal/peri-implant status (secondary outcomes) · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented for any of the pre-specified secondary outcomes. Follow-up visits registered pocket depth, bleeding on probing and mobility but the data were not reported.0 studiesNo studies
Metal-free FDPs (lithium disilicate) vs Metal-ceramic FDPs
Aesthetic evaluation · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented with regard to aesthetics.0 studiesNo studies
Metal-free FDPs (zirconia ceramic) vs Metal-ceramic FDPs
Periodontal/peri-implant status (secondary outcomes) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented for any of the pre-specified secondary outcomes. The trial registered pocket depth, bleeding on probing and mobility at follow-up visits but did not report the data.0 studiesNo studies
Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)
Aesthetic evaluation · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented with regard to aesthetics.0 studiesNo studies
Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns
Aesthetic evaluation · Adults (18 years or older) needing a single crown in the molar or premolar region
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented with regard to aesthetics.0 studiesNo studies
Metal-free FDPs (lithium disilicate) vs Metal-ceramic FDPs
Periodontal/peri-implant status and occlusal wear (secondary outcomes) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
Metal‐free materials for fixed prosthodontic restorations (2017) · Cochrane
No data were presented for any of the pre-specified secondary outcomes.0 studiesNo studies