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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,344 questions in 217 reviews · Oral Health
current versionsNo studies 1,344 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lingual nerve retractor (subperiosteal or Free's) vs No retractor Swelling · Adults with mandibular third molars requiring removal · 7 days Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water Incidence of symptomatic or test-positive COVID-19 infection in HCWs · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection · Minimum 2 weeks Use of antimicrobial mouthwashes (gargling) and nasal sprays by healthcare workers to protect them when… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Surgical drain (tube or gauze) vs No drain Wound infection · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Amoxicillin + clavulanate + SRP vs SRP Patient-reported quality of life changes · Adults with chronic periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Clinical examination with 24-month recall vs Clinical examination with 12-month recall Oral-health-related quality of life · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk) · 2 years Recall intervals for oral health in primary care patients (2020) · Cochrane | Summary of findings 1 lists 'Oral-health-related quality of life: Not reported' for the 24-month versus 12-month comparison (Wang 1992 did not measure it). | 0 studies | No studies |
Surgical drain (tube or gauze) vs No drain Alveolar osteitis · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
The wand (computer-controlled LA delivery system) vs Traditional local anaesthetic Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional) Wound infection · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
The wand (computer-controlled LA delivery system) vs Traditional local anaesthetic Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Acceptance of LA: included studies did not report on this outcome | NR | No studies |
Topical triamcinolone acetonide vs Topical tacrolimus Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment · 3-8 weeks Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane | Summary of findings 2: 'No data for this outcome' (triamcinolone vs tacrolimus, pain resolution) | 0 studies | No studies |
Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment, saline, or water Anosmia (or disturbance in sense of smell) · Patients with suspected or confirmed COVID-19 infection · Minimum 2 weeks Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Amoxicillin + metronidazole + SRP vs SRP Antimicrobial resistance · Adults with periodontitis (chronic and aggressive) · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Tetracycline + SRP vs SRP Adverse events · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included study has not reported adverse events | NR | No studies |
Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation) Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do) Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Clindamycin + SRP vs SRP Antimicrobial resistance · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Doxycycline + SRP vs SRP Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Horizontal mattress / fibrin sealant suturing vs Conventional (simple interrupted) suturing Swelling · Adults with mandibular third molars requiring removal · 7 days Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Counter-stimulation or distraction vs Conventional treatment Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before or during LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Counter-stimulation or distraction vs Conventional treatment Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before or during LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Camouflage syringe vs Conventional syringe Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods Reduction in volume of contaminated aerosols in the operative environment · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental… Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | Reduction in volume of contaminated aerosols in the operative environment: Not reported (row present in all Summary of findings tables) | 0 studies | No studies |
Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation) Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs Placebo or usual care Cost / economic data · Critically ill patients (adults and children) receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2020) · Cochrane | The outcome of cost was not reported by any study in this comparison. | 0 studies | No studies |
Pre-cooling of the injection site vs Conventional treatment Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment, saline, or water Change in COVID-19 viral load in patients · Patients with suspected or confirmed COVID-19 infection Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Azithromycin + SRP vs SRP Antimicrobial resistance · Adults with periodontitis (chronic and aggressive) · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Camouflage syringe vs Conventional syringe Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Acceptance of LA: included studies did not report on this outcome | NR | No studies |
Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment, saline, or water RECOVERY trial outcomes (mortality; hospitalisation status; use of ventilation; use of renal dialysis or haemofiltration) · Patients with suspected or confirmed COVID-19 infection · Minimum 2 weeks Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Audiovisual distraction vs Conventional treatment Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Doxycycline + SRP vs SRP Antimicrobial resistance · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Doxycycline + SRP vs SRP Adverse events · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included study has not reported adverse events | NR | No studies |
Clindamycin + SRP vs Doxycycline + SRP Patient-reported quality of life changes · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Clindamycin + SRP vs Metronidazole + SRP Adverse events · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included study has not reported adverse events | NR | No studies |
Surgical drain (tube or gauze) vs No drain Temporary altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal · ~1 month Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Azithromycin + SRP vs SRP Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive) · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Pre-cooling of the injection site vs Conventional treatment Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Acceptance of LA: included studies did not report on this outcome | NR | No studies |
Metronidazole + SRP vs SRP Antimicrobial resistance · Adults with periodontitis (chronic and aggressive) · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system) Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Pre-cooling of the injection site vs Conventional treatment Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water Other adverse events: allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection Use of antimicrobial mouthwashes (gargling) and nasal sprays by healthcare workers to protect them when… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Surgical drain (tube or gauze) vs No drain Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal · >6 months Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Hypnosis vs Conventional treatment Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before or during LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics) Cost / economic data · Critically ill adults receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2020) · Cochrane | The outcome of cost was not reported by any study in this comparison. | 0 studies | No studies |
Ionisation (ionic air purifier) vs No ionisation / standard operatory Outcome NR · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental… Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | no estimate extracted | 0 studies | No studies |
Doxycycline + SRP vs SRP Percentage of closed pockets · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Horizontal mattress / fibrin sealant suturing vs Conventional (simple interrupted) suturing Adverse effects · Adults with mandibular third molars requiring removal · up to 30 days Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Doxycycline + SRP vs Metronidazole + SRP Percentage of closed pockets · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Bone removal technique (chisel / piezoelectric / ultrasonic) vs Bur (conventional rotary) Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal · >6 months Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods Incidence of infection of dental staff or patients · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental… Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | Rate of infection of dental staff or patients: Not reported (row present in all Summary of findings tables) | 0 studies | No studies |