What do systematic reviews say?

Quality of sleep · adults with central sleep apnoea associated with heart failure

Quality of life · adults with central sleep apnoea associated with heart failure

All‐cause mortality · adults with central sleep apnoea associated with heart failure

Cardiovascular mortality · adults with primary central sleep apnoea

Serious adverse events · adults with primary central sleep apnoea

Quality of sleep · adults with primary central sleep apnoea

Quality of life · adults with primary central sleep apnoea

All‐cause mortality · adults with primary central sleep apnoea

Serious adverse events · adults with central sleep apnoea associated with heart failure

Quality of sleep · adults with central sleep apnoea associated with heart failure

Quality of life · adults with central sleep apnoea associated with heart failure

All‐cause mortality · adults with central sleep apnoea associated with heart failure

Change in class of malocclusion · people with thalassaemia (any age)

Resolution or reduction in severity of any other dental complication: reduction in DMFT index · people with thalassaemia (any age)

Resolution or reduction in severity of any other dental complication: reduction in severity of periodontitis (measured by reduction in clinical attachment loss) · people with thalassaemia (any age)

Resolution or reduction in severity of any other dental complication: oral infections (measured by reduction in or resolution of lesions such as periapical cysts, abscesses, or space infections) · people with thalassaemia (any age)

Resolution or reduction in severity of any other dental complication: systemic infections (measured by number of episodes after treatment for dental complications under antibiotic prophylaxis) · people with thalassaemia (any age)

Any other adverse effects related to treatment · people with thalassaemia (any age)

Quality of life ‐ not measured · stage III and IV cutaneous melanoma

Quality of life ‐ not measured · stage III and IV cutaneous melanoma