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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
504 questions in 57 reviews · Kidney and Transplant
current versionsNo studies 504 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Leflunomide vs methotrexate Dialysis · adults with renal vasculitis for maintenance therapy Interventions for renal vasculitis in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Cytotoxic regimen vs no cytotoxic regimen GFR loss ≥ 50% · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
MMF regimen vs no MMF regimen Death (any cause) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Calcineurin inhibitor regimen vs no calcineurin inhibitor regimen End‐stage kidney disease · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Calcineurin inhibitor regimen vs no calcineurin inhibitor regimen GFR loss ≥ 50% · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Calcineurin inhibitor regimen vs no calcineurin inhibitor regimen Annual GFR loss (mL/min/ 1.73 m2) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Calcineurin inhibitor regimen vs no calcineurin inhibitor regimen Death (any cause) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Mizoribine regimen vs no mizoribine regimen GFR loss ≥ 50% · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Mizoribine regimen vs no mizoribine regimen Annual GFR loss (mL/min/1.73 m2) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Mizoribine regimen vs no mizoribine regimen Death (any cause) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Leflunomide regimen vs no leflunomide regimen GFR loss ≥ 50% · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Leflunomide regimen vs no leflunomide regimen Annual GFR loss (mL/min/1.73 m2) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Leflunomide regimen vs no leflunomide regimen Death (any cause) · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Leflunomide regimen vs no leflunomide regimen Malignancy · adults and children who have IgA nephropathy proven on renal biopsy Immunosuppressive agents for treating IgA nephropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics Hyperkalaemia · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics Death · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics Cardiovascular events · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics Doubling serum creatinine · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics AKI · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers Kidney failure · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers Hyperkalaemia · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers Death · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers Cardiovascular events · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers Doubling serum creatinine · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers AKI · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs calcium channel blockers eGFR (mL/min/1.73 m²) · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs ACEi or ACEi plus ARB Kidney failure · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs ACEi or ACEi plus ARB Death · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs ACEi or ACEi plus ARB Cardiovascular events · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs ACEi or ACEi plus ARB Doubling serum creatinine · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs ACEi or ACEi plus ARB AKI · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate Kidney failure · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate Hyperkalaemia · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate Death · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate Cardiovascular events · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate Doubling serum creatinine · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate AKI · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonist vs nitrate eGFR · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist Kidney failure · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist Cardiovascular events · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist AKI · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist Proteinuria · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist eGFR · proteinuric chronic kidney disease Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
Aldosterone antagonists vs diuretics Kidney failure · proteinuric CKD Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression… (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs placebo Delayed graft function · pre‐existing and new‐onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs placebo Death (any cause) · pre‐existing and new‐onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs insulin glargine Transplant or graft survival · pre‐existing and new onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs insulin glargine Delayed graft function · pre‐existing and new onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs insulin glargine Kidney function markers · pre‐existing and new onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |
DPP‐4 inhibitors vs insulin glargine Death (any cause) · pre‐existing and new onset diabetes in kidney transplant recipients Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients (2020) · Cochrane | no estimate extracted | NR | No studies |