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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
321 questions in 77 reviews · Dental caries
current versionsNo studies 321 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental fillings (restorations) vs Dental extractions Outcome NR · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic… · Minimum 6 months follow-up Dental fillings for the treatment of caries in the primary dentition (2009) · Cochrane | "No studies were found that compared restorations versus extractions or no treatment as an intervention in children with caries in the primary dentition." | NR | No studies |
Dental fillings (restorations) vs No treatment Outcome NR · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic… · Minimum 6 months follow-up Dental fillings for the treatment of caries in the primary dentition (2009) · Cochrane | "No studies were found that compared restorations versus extractions or no treatment as an intervention in children with caries in the primary dentition." | NR | No studies |
Prefabricated metal post and core (Category II) vs Metal custom-cast post and core (Category I) Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned) Root canal posts for the restoration of root filled teeth (2007) · Cochrane | No included trial compared metal-cast posts with prefabricated metal posts (a planned primary comparison); no eligible study identified. | 0 studies | No studies |
Metal post of one alloy type vs Metal post of a different alloy type Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned) Root canal posts for the restoration of root filled teeth (2007) · Cochrane | No included trial evaluated alloy type in metal posts (a planned secondary comparison); no eligible study identified. | 0 studies | No studies |
Cast post and core with a diaphragm vs Cast post and core without a diaphragm Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned) Root canal posts for the restoration of root filled teeth (2007) · Cochrane | No included trial evaluated the presence of a diaphragm in cast posts (a planned secondary comparison); no eligible study identified. | 0 studies | No studies |
Post and core restoration with a ferrule vs Post and core restoration without a ferrule Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned) Root canal posts for the restoration of root filled teeth (2007) · Cochrane | No included trial evaluated the presence of a ferrule (a planned secondary comparison); no eligible study identified. | 0 studies | No studies |
Direct resin composite veneer vs Indirect resin composite veneer Adverse reactions · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Planned outcome; no adverse-reaction data were reported by the included trial. | 0 studies | No studies |
Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen) vs Fluoride toothpaste alone Enamel fluorosis (adverse effect) · Children or adolescents aged 16 years or less Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane | Fluorosis data have not been reported in any of the trials. | 0 studies | No studies |
Direct resin composite veneer vs Indirect resin composite veneer Pain following treatment · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Planned outcome; pain following treatment was not reported by the included trial (earlier trial publications reported treatment times, not pain). | 0 studies | No studies |
Direct resin composite veneer vs Indirect resin composite veneer Cost of treatment · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Planned outcome; cost of treatment was not reported by the included trial. | 0 studies | No studies |
Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group) Further conventional dental treatment (filling and drilling) (binary yes/no) · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any… Ozone therapy for the treatment of dental caries (2004) · Cochrane | Data were not provided by any study on the number of lesions requiring restorations to 6 months or later; no data on any further conventional treatment or other dental interventions. | NR | No studies |
Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group) Cost · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any… Ozone therapy for the treatment of dental caries (2004) · Cochrane | No data were provided in any of the included trials on costs. | NR | No studies |
Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group) Pain (assessed by the patient) · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any… Ozone therapy for the treatment of dental caries (2004) · Cochrane | No data were provided in any of the included trials on pain. | NR | No studies |
Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group) Time to intervention · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any… Ozone therapy for the treatment of dental caries (2004) · Cochrane | No data were provided in any of the included trials on time to intervention. | NR | No studies |
Direct resin composite veneer vs Indirect resin composite veneer Colour match (aesthetic achievement) · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Planned outcome; colour match was not reported by the single included trial (Meijering 1998). | 0 studies | No studies |
Ceramic inlays (all types) vs Composite resin inlay Outcome NR · Adults who require restorative treatment in posterior teeth Ceramic inlays for restoring posterior teeth (2003) · Cochrane | One randomised controlled trial (Gladys 1995) compared ceramic and resin composite inlays over 3 years, but it was excluded because the study design (parallel-group or split-mouth) was not clearly described; no… | 0 studies | No studies |
Ceramic inlays (all types) vs Amalgam Outcome NR · Adults who require restorative treatment in posterior teeth Ceramic inlays for restoring posterior teeth (2003) · Cochrane | No eligible randomised controlled trial comparing ceramic inlays with amalgam restorations was identified; this planned comparison could not be evaluated. | 0 studies | No studies |
Fluoride toothpaste vs Placebo (non-fluoride) toothpaste Enamel fluorosis (adverse effect) · Children and adolescents aged 16 years or less · At least 1 year Fluoride toothpastes for preventing dental caries in children and adolescents (2003) · Cochrane | Fluorosis data have not been reported in any of the trials. | 0 studies | No studies |
Ceramic inlays (all types) vs Gold inlay Aesthetic satisfaction (colour match) · Adults who require restorative treatment in posterior teeth Ceramic inlays for restoring posterior teeth (2003) · Cochrane | Information on aesthetic satisfaction could not be obtained from this study as it did not use the tooth-coloured restorations as the control group. | 0 studies | No studies |
Topical fluoride therapy (toothpaste, mouthrinse, gel or varnish; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Dental fluorosis · Children and adolescents aged 16 years or younger Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and… (2003) · Cochrane | Fluorosis data have not been reported in any of the trials. | 0 studies | No studies |
Ceramic inlays (all types) vs Composite resin (direct restoration) Outcome NR · Adults who require restorative treatment in posterior teeth Ceramic inlays for restoring posterior teeth (2003) · Cochrane | No eligible randomised controlled trial comparing ceramic inlays with composite resin (direct) restorations was identified; this planned comparison could not be evaluated. | 0 studies | No studies |