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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

531 questions in 102 reviews · Gynaecology and Fertility

current versions
No studies 531 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Metformin vs metformin combined with oral contraceptive pill (OCP)
Acne ‐ Visual analogue scale/Clinical acne score · adult women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Oral contraceptive pill (OCP) vs metformin combined with OCP
Improved menstrual pattern · aAdult women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs oral contraceptive pill (OCP)
Adverse event ‐ Severe · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs oral contraceptive pill (OCP)
Improved menstrual pattern · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs oral contraceptive pill (OCP)
Acne ‐ Visual analogue scale or Clinical acne score · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Hirsutism ‐ Clinical F‐G score · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Adverse event ‐ Severe · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Adverse event ‐ Minor · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Improved menstrual pattern · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Acne ‐ Visual analogue scale or Clinical acne score · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs oral contraceptive pill (OCP)
Adverse events ‐ Minor · adult women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
BMI (kg/m2) · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Oral contraceptive pill (OCP) vs metformin combined with OCP
Adverse events ‐ Minor · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Oral contraceptive pill (OCP) vs metformin combined with OCP
Improved menstrual pattern · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Oral contraceptive pill (OCP) vs metformin combined with OCP
Acne ‐ Visual analogue scale or Clinical acne score · adolescent women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Metformin vs metformin combined with oral contraceptive pill (OCP)
Adverse events ‐ Minor · adult women with PCOS
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in… (2020) · Cochrane
no estimate extractedNRNo studies
Natural cycle vs programmed cycle
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Natural cycle vs programmed cycle
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Transdermal oestrogens vs oral oestrogens
Live birth rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Transdermal oestrogens vs oral oestrogens
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Transdermal oestrogens vs oral oestrogens
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Transdermal oestrogens vs oral oestrogens
Endometrial thickness (mm) · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Transdermal oestrogens vs oral oestrogens
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Starting administration of the progestogen earlier vs starting administration of the progestogen later
Live birth rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Starting administration of the progestogen earlier vs starting administration of the progestogen later
Endometrial thickness · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Starting administration of the progestogen earlier vs starting administration of the progestogen later
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs control
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs control
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Among different GnRH agonists vs placebo
Live birth rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Among different GnRH agonists vs placebo
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Stimulated cycle vs programmed
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Among different GnRH agonists vs placebo
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Among different GnRH agonists vs placebo
Endometrial thickness (mm) · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Among different GnRH agonists vs placebo
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs GnRH antagonists
Live birth rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs GnRH antagonists
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs GnRH antagonists
Endometrial thickness (mm) · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
GnRH agonists vs GnRH antagonists
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Stimulated cycle vs programmed
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Aspirin vs control
Miscarriage rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Aspirin vs control
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Aspirin vs control
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Aspirin vs control
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Steroids vs control
Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Steroids vs control
Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Steroids vs control
Endometrial thickness (mm) · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Steroids vs control
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Stimulated cycle vs programmed
Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from… (2020) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events ‐ Multiple pregnancy · women with subfertility
Antioxidants for female subfertility (2020) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events ‐ Gastrointestinal disturbances · women with subfertility
Antioxidants for female subfertility (2020) · Cochrane
no estimate extractedNRNo studies