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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
281 questions in 50 reviews · Gynaecological, Neuro-oncology and Orphan Cancer
current versionsNo studies 281 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings: Evening RT vs morning RT Mean GI symptom scores · Women undergoing RT for cervical cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Evening RT vs morning RT QOL scores · Women undergoing RT for cervical cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Hydrogel spacer vs no intervention Mean GI symptom scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Hydrogel spacer vs no intervention Diarrhoea (grade 2+) · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Hydrogel spacer vs no intervention QOL scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Endorectal balloon vs no intervention Mean GI symptom scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Endorectal balloon vs no intervention QOL scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Aminosalicylates vs placebo Mean GI symptom scores (IBDQ‐B) · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Aminosalicylates vs placebo Diarrhoea (grade 2+) · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Aminosalicylates vs placebo QOL scores · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Superoxide dismutase vs no intervention Mean GI symptom scores · People with rectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Superoxide dismutase vs no intervention Diarrhoea (grade 2+) · People with rectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Superoxide dismutase vs no intervention QOL scores · People with rectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Corticosteroids vs placebo Mean GI symptom scores · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Corticosteroids vs placebo Diarrhoea (grade 2+) · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Corticosteroids vs placebo QOL scores · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Sucralfate vs placebo Mean GI symptom scores · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Sucralfate vs placebo QOL scores · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Amifostine vs no intervention Mean GI symptom scores · People with urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Amifostine vs no intervention QOL scores · People with urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Sodium butyrate vs placebo Mean GI symptom scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Sodium butyrate vs placebo Diarrhoea (grade 2+) · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Sodium butyrate vs placebo QOL scores · Men undergoing RT for prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Selenium vs no intervention Mean GI symptom scores · Women undergoing RT for gynecological cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Selenium vs no intervention Acute and late GI toxicity (grade 2+) · Women undergoing RT for gynecological cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Selenium vs no intervention QOL scores · Women undergoing RT for gynecological cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Bile acid sequestrants vs no intervention QOL scores · People with pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Misoprostol vs placebo Outcomes1 · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Misoprostol vs placebo Mean GI symptom scores · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Misoprostol vs placebo QOL scores · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Magnesium oxide vs placebo Mean GI symptom scores (during RT) · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Magnesium oxide vs placebo Diarrhoea (grade 2+) · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Magnesium oxide vs placebo QOL scores · Men with prostate cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Octreotide vs placebo Outcomes1 · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Octreotide vs placebo Mean GI symptom scores · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Octreotide vs placebo Acute and late GI toxicity (grade 2+) · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Octreotide vs placebo QOL scores · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Elemental diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Acute and late GI toxicity (grade 2+) · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Lactose‐restricted diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet High‐fibre diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Low‐fibre diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Low‐fat diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Diarrhoea · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Diet interventions vs usual on‐treatment diet Prebiotic diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Protein supplements vs no intervention Mean GI symptom scores (lower is better) · Individuals undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Protein supplements vs no intervention Acute and late GI toxicity (grade 2+) · Individuals undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Protein supplements vs no intervention QOL scores · Individuals undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Probiotics vs control (placebo or no intervention) Mean GI symptom scores · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Probiotics vs control (placebo or no intervention) Acute and late GI toxicity (grade 2+) · People undergoing RT for pelvic cancer Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane | no estimate extracted | NR | No studies |