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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

420 questions in 57 reviews · Gut

current versions
No studies 420 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Adalimumab vs active comparator
Serious adverse events · People with quiescent Crohn's disease (ileocolic resection)
Adalimumab for maintenance of remission in Crohn's disease (2020) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs active comparator
Withdrawal due to adverse events · People with quiescent Crohn's disease (ileocolic resection)
Adalimumab for maintenance of remission in Crohn's disease (2020) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs active comparator
Failure to maintain clinical or endoscopic response with prior TNF‐α antagonist exposure · People with quiescent Crohn's disease (ileocolic resection)
Adalimumab for maintenance of remission in Crohn's disease (2020) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs active comparator
Failure to maintain clinical remission · People with quiescent Crohn's disease (ileocolic resection)
Adalimumab for maintenance of remission in Crohn's disease (2020) · Cochrane
no estimate extractedNRNo studies
Rifaximin vs placebo
Maintenance of clinical remission · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Rifaximin vs placebo
No episodes acute pouchitis · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Lactobacillus GG vs placebo
Clinical remission · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Lactobacillus GG vs placebo
Maintenance of clinical remission · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Lactobacillus GG vs placebo
No episodes acute pouchitis · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Ciprofloxacin vs metronidazole
Clinical improvement · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Lactobacillus GG vs placebo
Adverse events · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Glutamine vs butyrate
Clinical remission · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Glutamine vs butyrate
Clinical improvement · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Glutamine vs butyrate
No episodes acute pouchitis · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Glutamine vs butyrate
Adverse events · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bismuth enema vs placebo
Clinical remission · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bismuth enema vs placebo
Maintenance of clinical remission · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bismuth enema vs placebo
No episodes acute pouchitis · Patients with chronic pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Ciprofloxacin vs metronidazole
Maintenance of clinical remission · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs placebo
Clinical remission · Patients with chronic pouchitis or ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs placebo
Clinical improvement · Patients with chronic pouchitis or ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs no treatment
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs no treatment
Clinical improvement · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs no treatment
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Ciprofloxacin vs metronidazole
No episodes acute pouchitis · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
De Simone Formulation vs no treatment
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bifidobacterium longum vs placebo
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bifidobacterium longum vs placebo
Clinical improvement · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bifidobacterium longum vs placebo
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Bifidobacterium longum vs placebo
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Clinical improvement · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Tinidazole vs placebo
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Tinidazole vs placebo
Clinical improvement · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Tinidazole vs placebo
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Tinidazole vs placebo
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs placebo
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs placebo
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs placebo
No of episodes of acute pouchitis · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Adalimumab vs placebo
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Clostridium probiotic vs placebo
Clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Clostridium probiotic vs placebo
Clinical improvement · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Clostridium probiotic vs placebo
Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Clostridium probiotic vs placebo
Adverse events · Patients with ileal pouch‐anal anastomosis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Metronidazole vs budesonide enema
Maintenance of clinical remission · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
Metronidazole vs budesonide enema
No episodes acute pouchitis · Patients with acute pouchitis
Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis (2019) · Cochrane
no estimate extractedNRNo studies
5‐ASAs vs placebo
Radiologic relapse · people with surgically‐induced remission in Crohn's disease
Oral 5‐aminosalicylic acid for maintenance of surgically‐induced remission in Crohn's disease (2019) · Cochrane
no estimate extractedNRNo studies
5‐ASAs vs placebo
Health related quality of life · people with surgically‐induced remission in Crohn's disease
Oral 5‐aminosalicylic acid for maintenance of surgically‐induced remission in Crohn's disease (2019) · Cochrane
no estimate extractedNRNo studies