What do systematic reviews say?

Adverse events · patients with diarrhoea due to Shiga toxin‐producing E. coli

Need for acute dialysis · paediatric patients with diarrhoea due to Shiga toxin‐producing E. coli

Need for acute dialysis · patients with diarrhoea due to Shiga toxin‐producing E. coli

Neurological complications · patients with diarrhoea due to Shiga toxin‐producing E. coli

Death (any cause) · patients with diarrhoea due to Shiga toxin‐producing E. coli

Need for acute dialysis · patients with diarrhoea due to Shiga toxin‐producing E. coli

Neurological complications · patients with diarrhoea due to Shiga toxin‐producing E. coli

Clinical impression: severity ‐ not reported · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Clinical impression: improvement‐ not reported · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Harms: adverse events (poorly assessed and reported) · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Harms: adverse events (poorly assessed and reported) · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Efficacy (changes in symptoms of ADHD): participant‐rated ‐ not reported · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Near vision · people with non‐exudative AMD (AREDS 2 to 4)

Low luminance deficit score · people with non‐exudative AMD (AREDS 2 to 4)

Reading speed (words per minute) · people with non‐exudative AMD (AREDS 2 to 4)

Primary rehabilitation · Chronic respiratory disease

Primary rehabilitation · Chronic respiratory disease

Health‐related quality of life · people (of any age) with CSOM

Hearing · people (of any age) with CSOM

Resolution of ear discharge ‐ measured at 1 to 2 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…