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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

70 questions in 8 reviews · Temporomandibular disorders and sleep

current versions
No studies 70 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Iontophoretically applied corticosteroids
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
The review noted the noticeable absence of evidence for iontophoretically applied corticosteroids; no eligible RCT evaluated it (Discussion).0 studiesNo studies
Physiotherapy modalities (physiotherapy, short-wave diathermy, ultrasound)
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
The review noted the noticeable absence of evidence for physiotherapy, short-wave diathermy and ultrasound; no eligible RCT evaluated these (Discussion).0 studiesNo studies
Open TMJ surgery (arthroplasty / total joint replacement)
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
No study evaluated open surgery for TMJ OA, which should be explored in future trials (Research recommendations Table 1; Discussion).0 studiesNo studies
Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance
Patient quality of life · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms) · At least 6 months after the intervention
Orthodontics for treating temporomandibular joint (TMJ) disorders (2010) · Cochrane
no estimate extracted0 studiesNo studies
Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance
Adverse effects on oral health · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms) · At least 6 months after the intervention
Orthodontics for treating temporomandibular joint (TMJ) disorders (2010) · Cochrane
no estimate extracted0 studiesNo studies
Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance
Limitation of movement · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms) · At least 6 months after the intervention
Orthodontics for treating temporomandibular joint (TMJ) disorders (2010) · Cochrane
no estimate extracted0 studiesNo studies
Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance
Development of TMD (onset/incidence of signs and symptoms) · People without TMD at baseline undergoing orthodontic treatment (TMD clinically absent at baseline); no age… · Follow-up period extended into adulthood
Orthodontics for treating temporomandibular joint (TMJ) disorders (2010) · Cochrane
no estimate extracted0 studiesNo studies
Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance
Overall symptoms, pain and headache (relief from symptoms assessed by global measures) · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms) · At least 6 months after the intervention
Orthodontics for treating temporomandibular joint (TMJ) disorders (2010) · Cochrane
no estimate extracted0 studiesNo studies
Arthrocentesis and lavage vs Arthroscopy
Temporomandibular joint tenderness · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without…
Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane
To date, no randomised controlled trial in this area reported temporomandibular joint tenderness.0 studiesNo studies
Arthrocentesis and lavage vs Arthroscopy
Quality of life · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without…
Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane
No data about quality of life were reported by the included trials.0 studiesNo studies
Arthrocentesis and lavage vs Arthroscopy
Deviation of the mandible · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without…
Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane
To date, no randomised controlled trial in this area reported deviation of the mandible.0 studiesNo studies
Arthrocentesis and lavage vs Arthroscopy
Muscular tenderness · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without…
Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane
To date, no randomised controlled trial in this area reported muscular tenderness.0 studiesNo studies
Arthrocentesis and lavage vs Arthroscopy
Maximum bite force · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without…
Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane
To date, no randomised controlled trial in this area reported maximum bite force.0 studiesNo studies
Occlusal splint vs Pharmacological interventions (benzodiazepines, anticonvulsants, beta blockers, dopamine agents, antidepressants, botulinum toxin A and B, analgesics)
Outcome NR · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis…
Occlusal splints for treating sleep bruxism (tooth grinding) (2007) · Cochrane
Pharmacological interventions remained a planned comparator, but no included trial compared occlusal splint with any drug; no eligible study.0 studiesNo studies
Occlusal splint vs Behaviour therapy (sleep hygiene, relaxation, psychotherapy, hypnosis, biofeedback)
Outcome NR · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis…
Occlusal splints for treating sleep bruxism (tooth grinding) (2007) · Cochrane
Behaviour therapy remained a planned comparator, but no included trial compared occlusal splint with behaviour therapy; no eligible study.0 studiesNo studies
Occlusal splint vs Placebo
Outcome NR · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis…
Occlusal splints for treating sleep bruxism (tooth grinding) (2007) · Cochrane
Placebo remained a planned comparator in the review methods (Types of interventions), but none of the five included trials compared occlusal splint with placebo; no eligible study.0 studiesNo studies
Occlusal adjustment (OA) vs Placebo
Psychosocial outcomes · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD)
Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane
There were no data on psychosocial outcomes, costs or quality of life in any of the trials.0 studiesNo studies
Occlusal adjustment (OA) vs Placebo
Quality of life · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD)
Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane
There were no data on psychosocial outcomes, costs or quality of life in any of the trials.0 studiesNo studies
Occlusal adjustment (OA) vs Placebo
Adverse events · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD)
Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane
There were no reports of adverse reactions.0 studiesNo studies
Occlusal adjustment (OA) vs Placebo
Cost · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD)
Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane
There were no data on psychosocial outcomes, costs or quality of life in any of the trials.0 studiesNo studies