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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,344 questions in 217 reviews · Oral Health
current versionsNo studies 1,344 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Orthodontic treatment without extraction of permanent teeth (removable, fixed, or functional braces, or headgear) vs No treatment (or delayed treatment) Quality of life · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth) Orthodontic treatment for deep bite and retroclined upper front teeth in children (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
Formocresol (FC) pulpotomy vs Calcium hydroxide pulpectomy Outcome NR · Children with extensive decay involving the dental pulp in primary teeth Pulp treatment for extensive decay in primary teeth (2018) · Cochrane | Coser 2008 randomised 51 teeth; no data provided for any outcome | 0 studies | No studies |
2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: See comment; 0 participants (0 studies); 1 case of prolonged anaesthesia recorded; no clinical studies met the outcome definition (unable to confirm whether prolonged anaesthesia = paraesthesia). | 0 studies | No studies |
Sedation Outcome NR · Medically compromised children (ASA III+) or children with learning/behavioural difficulties needing dental treatment Sedation of children undergoing dental treatment (2018) · Cochrane | 'Some of the techniques described may be useful in the management of medically compromised patients, but at present there are no studies carried out in these groups.' (Discussion) Explicit evidence gap. | 0 studies | No studies |
Planned, regular routine scale and polish (6-monthly; 12-monthly parallel) vs No scheduled scale and polish treatment Halitosis · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental… Routine scale and polish for periodontal health in adults (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
Tooth-supported removable partial denture: different impression material, same final-impression technique vs The same technique with an alternative final-impression material Outcome NR · Partially edentulous people requiring a removable partial denture Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane | We did not find any trials for this comparison. | 0 studies | No studies |
Self-management (self-administered/self-monitored OHA) vs Professional OHA Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition) One‐to‐one oral hygiene advice provided in a dental setting for oral health (2018) · Cochrane | No studies were found that looked at dental caries. | 0 studies | No studies |
3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Routine scale and polish provided by a dentist vs Routine scale and polish provided by a dental care professional (dental therapist or hygienist) Gingivitis · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental… Routine scale and polish for periodontal health in adults (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Another active intervention, placebo, or no treatment Adverse events · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior,… Interventions for treating post‐extraction bleeding (2018) · Cochrane | No data are available as no RCTs have been conducted on interventions to treat post-extraction bleeding | 0 studies | No studies |
Late treatment (one-phase) with fixed functional appliance vs No treatment Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II… · End of orthodontic treatment Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children and adolescents (2018) · Cochrane | Incidence of incisal trauma: Not measured | NR | No studies |
2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine Speed of onset of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone Tooth loss · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane | Not measured | 0 studies | No studies |
3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Speed of onset of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Any attachment system for maxillary implant overdentures vs A different attachment system for maxillary implant overdentures Outcome NR · Edentulous adults receiving maxillary implant overdentures Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane | no estimate extracted | NR | No studies |
Slow-release fluoride device (fluoride glass beads) vs Placebo or usual care (control) Use of healthcare resources (cost effectiveness, time taken to fit, number of dental visits) · Children with high risk of dental decay Slow‐release fluoride devices for the control of dental decay (2018) · Cochrane | The study reported no data on use of healthcare resources | 0 studies | No studies |
4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Removable functional appliance vs Fixed functional appliance Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II… · End of orthodontic treatment Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children and adolescents (2018) · Cochrane | Incidence of Incisal trauma: Not measured | NR | No studies |
0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Slow-release fluoride device (fluoride glass beads) vs Placebo or usual care (control) Participant satisfaction · Children with high risk of dental decay Slow‐release fluoride devices for the control of dental decay (2018) · Cochrane | No RCT evidence found | 0 studies | No studies |
4% articaine, 1:100,000 epinephrine vs 2% mepivacaine, 1:100,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Orthodontic treatment without extraction of permanent teeth (removable, fixed, or functional braces, or headgear) vs No treatment (or delayed treatment) Dento-occlusal results of treatment, measured with the PAR index · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth) Orthodontic treatment for deep bite and retroclined upper front teeth in children (2018) · Cochrane | No data are available as no RCTs or CCTs have been conducted. | 0 studies | No studies |
Photodynamic therapy plus mechanical debridement vs Mechanical debridement alone Tooth loss · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane | Not measured | 0 studies | No studies |
Photodynamic therapy plus mechanical debridement vs Mechanical debridement alone Adverse events · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane | Not measured | 0 studies | No studies |
GTR rm associated with bone substitutes + CAF vs GTR rm + CAF Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm) · Short term (6 to 12 months) Root coverage procedures for treating localised and multiple recession‐type defects (2018) · Cochrane | Aesthetic condition change was not reported for this comparison | 0 studies | No studies |
Non-surgical technique A vs Non-surgical technique B Outcome NR · People of any age with oro-antral communications, fistulae, or both caused by dental procedures Interventions for treating oro‐antral communications and fistulae due to dental procedures (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice) Clinical attachment loss · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane | Not measured | 0 studies | No studies |
Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender · All follow-ups Autologous platelet concentrates for treating periodontal infrabony defects (2018) · Cochrane | No RBF (radiographic bone defect filling) data were available for the APC + GTR versus GTR comparison. | 0 studies | No studies |
0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Autologous platelet concentrates (APC) + open flap debridement (OFD) vs OFD (open flap debridement) alone Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender Autologous platelet concentrates for treating periodontal infrabony defects (2018) · Cochrane | No quantitative analysis regarding patients' quality of life was possible (no data). | 0 studies | No studies |
CP paint-on gel vs HP strips Adverse effects · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline… Home‐based chemically‐induced whitening (bleaching) of teeth in adults (2018) · Cochrane | Not reported | NR | No studies |
ADMG + CAF vs CAF Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm) · Short term (6 to 12 months) Root coverage procedures for treating localised and multiple recession‐type defects (2018) · Cochrane | Aesthetic condition change related to patient's opinion: Not reported (SoF 2) | 0 studies | No studies |
SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice) Adverse events · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane | Not measured | 0 studies | No studies |
3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine Speed of onset of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Another active intervention, placebo, or no treatment Treatment-associated average cost · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior,… Interventions for treating post‐extraction bleeding (2018) · Cochrane | No data are available as no RCTs have been conducted on interventions to treat post-extraction bleeding | 0 studies | No studies |
Zinc oxide and eugenol (ZOE) vs RC Fill Outcome NR · Children with extensive decay involving the dental pulp in primary teeth Pulp treatment for extensive decay in primary teeth (2018) · Cochrane | Listed as a pulpectomy comparison; no extractable outcome data reported in this version | 0 studies | No studies |
Endoflas (CH + ZOE + iodoform) vs RC Fill Outcome NR · Children with extensive decay involving the dental pulp in primary teeth Pulp treatment for extensive decay in primary teeth (2018) · Cochrane | Listed as a pulpectomy comparison but no extractable outcome data reported in this version | 0 studies | No studies |
Planned, regular routine scale and polish (6-monthly; 12-monthly parallel) vs No scheduled scale and polish treatment Attachment change · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental… Routine scale and polish for periodontal health in adults (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
Mineral trioxide aggregate (MTA) vs IRM (intermediate restorative material) Outcome NR · Children with extensive decay involving the dental pulp in primary teeth Pulp treatment for extensive decay in primary teeth (2018) · Cochrane | Listed as a pulpectomy comparison; no extractable outcome data reported in this version | 0 studies | No studies |
Ball (stud) attachment system vs Magnetic attachment system Patient preference (cross-over trials) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane | no estimate extracted | NR | No studies |
2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | SoF: Not measured. | 0 studies | No studies |
Routine scale and polish provided by a dentist vs Routine scale and polish provided by a dental care professional (dental therapist or hygienist) Participant satisfaction · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental… Routine scale and polish for periodontal health in adults (2018) · Cochrane | no estimate extracted | 0 studies | No studies |
Planned, regular routine scale and polish (6-monthly; 12-monthly parallel) vs No scheduled scale and polish treatment Tooth loss · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental… Routine scale and polish for periodontal health in adults (2018) · Cochrane | no estimate extracted | 0 studies | No studies |