What do systematic reviews say?

Outcomes · newly‐diagnosed EOC

Adverse eventsb · sudden sensorineural hearing loss

Vertigo/dizziness: timing not reported · sudden sensorineural hearing loss

Ear pain: timing not reported · sudden sensorineural hearing loss

Adverse eventsb · sudden sensorineural hearing loss

Vertigo/dizziness: timing not reported · sudden sensorineural hearing loss

Ear pain: timing not reported · sudden sensorineural hearing loss

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Vertigo/dizziness: at the time of injection · sudden sensorineural hearing loss

Ear pain: at the time of injection · sudden sensorineural hearing loss

Adverse eventsb · sudden sensorineural hearing loss

Endometrial histology · young women with Turner syndrome who have completed pubertal induction

Uterine perfusion · young women with Turner syndrome who have completed pubertal induction

Reproductive outcomes · young women with Turner syndrome who have completed pubertal induction

Endometrial histology · women with premature ovarian insufficiency (POI) awaiting oocyte donation

Uterine perfusion · women with premature ovarian insufficiency (POI) awaiting oocyte donation

Endometrial thickness (mm) · girls with Turner syndrome who were treated with prepubertal growth hormone

Reproductive outcomes · women with premature ovarian insufficiency (POI) awaiting oocyte donation

Adverse events · women with premature ovarian insufficiency (POI) awaiting oocyte donation